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2023 1

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HMGCS2 1

SIRT5 1

ketogenesis 1

sodium butyrate 1

succinylation 1

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Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 339-351 doi: 10.1007/s11684-022-0943-0

Abstract: catalytic activity of 3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2), a rate-limiting enzyme in ketogenesis

Keywords： sodium butyrate     succinylation     HMGCS2     ketogenesis     SIRT5    

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Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation

Journal Article